For some people, hearing the word Botox paints a picture of a plastic woman with a frozen face. Other people think “rat poison”. What’s the reason behind all this negativity? In my opinion, there are two main reasons: Reality shows where someone went way too far and lack of knowledge.
Hopefully this post will alter any negative perspectives out there and turn them into positive ones.
Let’s start with the most basic questions…
What is Botox?
Botox (onabotulinumtoxinA) is a two-chain polypeptide protein and neurotoxin produced by a purified form of bacterium Clostridium botulinum.
“Purified” being the key word here…
Botox works to relax the contraction of muscles by blocking nerve impulses, resulting in muscles that can no longer contract, causing dynamic wrinkles (wrinkles that appear temporarily when a muscle contracts during facial expression) to relax and soften. It usually takes 2-14 days to see cosmetic improvement and the effects can last 3-6 months.
Who is Botox good for?
Botox is FDA approved for men and woman from ages 18-65. Although most think that Botox is for older people… It’s actually extremely preventative. More and more, people are starting to realize this fact. For example, take a look at your mother, father, or any other older person you may encounter… Do you see any permanent wrinkles in between their eyes? Those wrinkles are caused by the corrugator muscle contracting over and over again. This contraction causes collagen breakdown every time the muscle contracts. So, the earlier you start getting Botox the less wrinkling you’ll get later in life. The older you get, the more you’re doing it just to treat those wrinkles, the younger you are, the more you’re doing to prevent them from occurring.
Average cost is $200-$400 per area and should be repeated every 3-6 months for optimal long-term results. (I usually spend this amount every time I visit the supermarket)
Botox timeline of events:
1895 – Emile van Ermengem, Belgian bacteriologist, found the producer of the botulin toxin was a bacterium, which he named Clostridium botulinum.
1928 – P. Tessmer Snipe and Hermann Sommer for the first time purified the toxin.
1949 – Arnold Burgen discovered that botulinum toxin blocks neuromuscular transmission through decreased acetylcholine release.
1960’s – Alan Scott, M.D., a San Francisco ophthalmologist, and Edward Schantz were the first to work on a standardized botulinum toxin preparation for therapeutic purposes.
1973 – Scott (now at Smith-Kettlewell Institute) used botulinum toxin type A (BTX-A) in monkey experiments.
1980 – Botox was officially used for the first time in humans to treat strabismus “crossed eyes”, and “uncontrollable blinking”, blepharospasm.
1989 – The cosmetic effect of BTX-A on wrinkles was originally documented by a plastic surgeon from Sacramento, California, Dr. Richard Clark, and published in the journal Plastic and Reconstructive Surgery.
1993 – Discovered that botulinum toxin could be used for the treatment of achalasia, a spasm of the lower esophageal sphincter.
1994 – Dr. Khalaf Bushara of Southend Hospital in England, showed that botulinum toxin injections inhibit sweating. This was the first demonstration of non-muscular use of BTX-A in humans.
December 21, 2000 – Botulinum Toxin Type B (BTX-B) received FDA approval for treatment of cervical dystonia.
April 12, 2002 – The FDA announced regulatory approval of botulinum toxin type A (Botox Cosmetic) to temporarily improve the appearance of moderate-to-severe frown lines between the eyebrows (glabellar lines)
June 2009 – Its use for treating hypertonic muscles helped an Australian man to walk again. He had required a wheelchair for mobility following a stroke 20 years prior
October 15, 2010 – Received FDA approval for treatment of chronic migraines.
September 11, 2013 - Received FDA approval for crows feet.
Clearly, throughout the years, Botox has gone through many discoveries and has truly done and continues to do amazing things cosmetically and medically. To add on to this, here’s a full list of its cosmetic and non-cosmetic reported uses:
Cervical dystonia or spasmodic torticollis (a neuromuscular disorder involving the head and neck)
Blepharospasm (excessive blinking)
Severe primary axillary hyperhidrosis (excessive sweating)
Achalasia (failure of the lower oesophageal sphincter to relax)
Chronic focal neuropathies
Migraine and other headache disorders
Idiopathic and neurogenic detrusor overactivity
Incontinence due to overactive bladder
Incontinence due to neurogenic bladder
Vaginismus (to reduce the spasm of the vaginal muscles)
Movement disorders associated with injury or disease of the central nervous system including trauma, stroke, multiple sclerosis, Parkinson’s disease, or cerebral palsy
Focal dystonias affecting the limbs, face, jaw, or vocal cords
TMJ pain disorders
Vocal cord dysfunction (VCD) including spasmodic dysphonia and tremor
Reduction of the Masseter muscle for decreasing the apparent size of the lower jaw
Painful bladder syndrome
Detrusor sphincter dyssynergia and benign prostatic hyperplasia
The amount used for cosmetic purposes is an average of 15-30 units per area…
The amount used for non-cosmetic purposes is between 50-360 units per area…
The non-cosmetic amount is 12 times more than cosmetic amount used!
So as you can see, Botox offers a variety of solutions for a multitude of problems… cosmetically and medically.